Safety Update – product information updates
When new safety information comes to light about medicinal products, Swissmedic works closely with marketing authorisation holders to update the corresponding product information (Information for healthcare professionals and Patient information). As a result, healthcare professionals gain timely access to safety-related findings.
The following overview is updated monthly and provides information about selected active substances or active substance groups whose Information for healthcare professionals has been, or will be, updated with new safety-related information.
These updates are currently available in German, French, or Italian.
Important information
The updates to product information for generics are delayed as these are adapted at a later date to those of the original product. Please note that this is not a complete overview since not all changes to individual Information for healthcare professionals are presented in detail, and the safety information listed for individual medicinal products containing an active substance or substance class may already be included in the Information for healthcare professionals.
The information is subject to possible legal remedies. In all cases, the current versions of the Information for healthcare professionals available at www.swissmedicinfo-pro.ch are binding.
All Safety Updates since November 2025
Safety of medicines – always up to date
Subscribe to the newsletter
The “Safety of medicines” newsletter provides monthly updates on the most important revisions to the product information for selected active substances or substance groups.
| Wirkstoff(e) |
Neue Sicherheitsinformation |
Angepasste Rubrik(en) |
(D)HPC |
| Abemaciclib |
Kopfschmerzen |
Unerwünschte Wirkungen |
– |
| Calcineurin-Inhibitoren (systemisch) |
Kombination mit Johanniskraut (Hypericum perforatum) wegen klinisch relevanter Interaktion (Gefahr der Transplantatabstossung) vermeiden. |
Warnhinweise und Vorsichtsmassnahmen, Interaktionen |
– |
| mTOR-Inhibitoren |
Kombination mit Johanniskraut (Hypericum perforatum) wegen Interaktion nicht empfohlen. |
Interaktionen |
– |
| Tetracycline |
Fixes Arzneimittelexanthem |
Unerwünschte Wirkungen |
– |
